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60 Capsules

Ingredients and Benefits:

Each 400mg VegeCap contains:

Magnesium L-Threonate 100mg
Ginger 50mg
Feverfew 50mg
Arjuna Bark Extract 50mg
Butterbur 15% Petasin 50mg
Milk Thistle (80% Silymarin) 100mg

Dosage:

Take 2 capsules twice daily until symptoms subside then take 2 capsules with the morning meal.

Butterbur

For hundreds of years butterbur (Petasites hybridus) has been used against many diseases. Modern indications are the prophylaxis of migraine, tension headache, spasms of the urogenital tract, gastro-intestinal tract and bile duct. The petasines, the main components of butterbur, inhibit the synthesis of leucotrienes and decrease the intracellular concentration of calcium which explains the anti-inflammatory and spasmolytic properties of extracts of butterbur. Thanks to extraction with supercritical CO 2 (carbon dioxide) the concentrations of the potentially hepatotoxic and carcinogenic pyrrolizidine alkaloids (PA’s) lie below the detection limits.

Magnesium L-Threonate

Studies have found that people who have migraines tend to have lower levels of magnesium than people who don’t get headaches. Some scientists believe that magnesium blocks signals in the brain that lead to migraines with an aura, or changes in vision and other senses. Research also suggests that magnesium stops certain chemicals that cause pain. What’s more, a drop in magnesium levels also seems to cause blood vessels in the brain to narrow, or constrict, which may also play a role in migraine.

Feverfew Leaf

The Feverfew Leaf herb continues to undergo extensive scientific investigation of its parthenolide content, and how it normalizes the function of platelets in the blood system by inhibiting platelet aggregation, reducing serotonin release from platelets, and blocking the formation of pro-inflammatory mediators that can cause blood vessels to swell. 70% of the patients in these studies report fewer attacks of migraines and less painful attacks when they do occur. Researchers believe that feverfew prevents the spasms of blood vessels in the head that trigger migraines. This herb also relieves the inflammation associated with arthritis.

CoQ10 from Arjuna Bark

Thirty-two patients diagnosed as having migraine with or without aura were treated with CoQ10 at a dose of 150 mg per day in a controlled experiment10. No adverse events were associated with CoQ10 therapy in any of the trial participants. As a result of the treatment, 61.3% of the patients treated had a greater than 50% reduction in number of days with migraine headache. Only two participants showed no improvement with CoQ10 therapy in their migraine headache intensity compared with baseline (ie when the trial started). The average number of days with migraine headache during the baseline non-treatment phase was 7.34 and this decreased to 2.95 days by the end of the trial. The reduction in migraine frequency after 1 month of treatment was 13% and this improved to 55% by the end of 3 months of therapy. From this open-label (called “open” as participants were aware of whether they were taking CoQ10 or not) investigation, CoQ10 appears to be a good migraine preventive. The data presented in this trial suggest that CoQ10 starts to work within 4 weeks but usually takes 5 to 12 weeks to yield a significant reduction in days with migraine. An important finding from this study is that taking CoQ10 appears to be associated with no significant adverse events and is extremely well-tolerated. In another study11 migraine attack frequency after 4 months of treatment was reduced at least 50% in 48% of patients as compared to 14% for placebo. CoQ10 supplementation may be particularly effective in the treatment of childhood migraine12.

Ginger

Few studies to date have proposed ginger derivates for migraine relief. A recent study evaluated the efficacy of ginger in the ablation of common migraine attacks in comparison to sumatriptan therapy. In this double-blinded randomized clinical trial, 100 patients who had acute migraine without aura were randomly allocated to receive either ginger powder or sumatriptan. Time of headache onset, its severity, time interval from headache beginning to taking drug and patient self-estimation about response for five subsequent migraine attacks were recorded by patients. Patients satisfaction from treatment efficacy and their willingness to continue it was also evaluated after 1 month following intervention. Two hours after using either drug, mean headaches severity decreased significantly. Efficacy of ginger powder and sumatriptan was similar. Clinical adverse effects of ginger powder were less than sumatriptan. The effectiveness of ginger powder in the treatment of common migraine attacks is statistically comparable to sumatriptan. Ginger also poses a better side effect profile than sumatriptan.

Milk Thistle

Milk Thistle is a well-known and studied herb that enhances liver function and stimulates regeneration of hepatic cells when mild to moderately damaged. Due to the liver’s role in detoxifying the blood, and the possible role of toxins in the blood stimulating inflammation and abnormal contraction of the blood vessels, milk thistle has been shown to reduce the number of migraine attacks in chronic sufferers, possibly pointing to a link between digestion, elimination and the inflammation in the blood vessels.

Milk thistle seeds contain a group of flavonolignans–which are believed to be the plant’s active constituents, and as a group, are known as silymarin. Silymarin is a group of flavonolignans, and silybinin, the major constituent, along with isosilybin, dihydrosilybin, silydianin, silychristin, and a few flavonoids.

This information is provided for educational purposes only. All medical conditions must be diagnosed and treated by a qualified health professional. No medical claims are made.

 

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